Wednesday, May 6, 2020
Childhood Memories And Its Effects On Our Lives - 1173 Words
We each have memories, both from long ago and recent times, that we hold dear to us. Memories get us through the hard days and keep us chipper in the good ones. The past is what makes us who we are. It shapes how we act, how we treat others, and simply just what we do on a day to day basis. Memories are the little things that keep this world running smoothly. Imagine what it would be like to lose those memories. What if you were to forget things to the point you were losing your functionality? Every 67 seconds another person in the US falls victim to this disease (www.alz.org). They may remember childhood memories, but forgot where they put the cheese they bought yesterday. As the disease gets worse and worse, they may wander and even forget people they care deeply about and those they interact with daily. Who are these people, and what is the ââ¬Å"itâ⬠they are suffering from? These are people suffering from Alzheimers Disease, affecting 5 million individuals in the United States alone. Alzheimers Disease is a type of dementia, a more general term meaning a decline in someoneââ¬â¢s mental ability, to the point of affecting their everyday life. Alzheimers is actually the most common form, afflicting about 80% of dementia patients. There are treatments and medications available to help patients with symptoms and slow its progress through the brain, but science has not yet found a way to completely stop it, or even slow it significantly for many patients. As patients continueShow MoreRelatedThe Lifelong Health Effects Of Childhood Trauma1301 Words à |à 6 PagesThe topic that I have decided to write about is childhood trauma. I wanted to research the lifelong health effects that are caused by childhood trauma. One thing that has always concerned me is the life of children growing up in war-zones or areas with extreme poverty and crime. I assume that there is a correlation between traumatic experiences and health. Many people would argue that the cor relation behind it is that it is more likely that a person makes bad health decisions like drinking and doingRead MoreIntegrated Analysis Of Service Learning Age Group Late Childhood Essay1368 Words à |à 6 PagesIntroduction: Throughout the course of this semester, we discovered the wonders of how the mind and body develop over time. How our brains can grow in knowledge of problem solving skills and how our bodies capabilities decline in older adulthood. In this semester, I focused on one portion of development in particular. I chose to concentrate on late childhoodââ¬âaround ages ten to twelveââ¬âbecause I had no prior knowledge of this age group other than my own personal experiences. My service learning experienceRead MorePoems to Reminisce Childhood1443 Words à |à 6 Pagesor reminiscing over it, everyone experiences childhood; the experience elicits a large spectrum of emotions from every reader. The poems ââ¬ËPoem at Thirty-Nineââ¬â¢ by Alice Walker, ââ¬ËOnce Upon a Timeââ¬â¢ by Gabriel Okara, and ââ¬ËPianoââ¬â¢ by D.H. Lawrence explore the theme of childhood from different perspectives. In ââ¬ËOnce Upon A Timeââ¬â¢, Okara explores childhood as a time of vulnerabil ity, where safety and protection are needed. Walkerââ¬â¢s ââ¬ËPoem at 39ââ¬â¢ views childhood as a time when one can start to progress to theirRead MoreEssay about The Psychodynamic Model of Abnormality1148 Words à |à 5 Pagesabnormality but also normality. Freud developed Psychoanalysis. This is a set of techniques for treating the unconscious causes of mental disorders and built up a psychoanalytic theory of how human personality and abnormality develop from childhood. His psychoanalytic approach had a great impact on psychology and psychiatry and was developed by other psychodynamic theorists. Psychoanalysis had a very fixed set of assumptions. One of these is the unconscious processes whereRead MorePoem at 39 by Alice Walker1164 Words à |à 5 PagesIn ââ¬ËPoem at 39ââ¬â¢ by Alice Walker, the persona reminisces over her childhood with a melancholic stance, while still viewing itââ¬â¢s overall impact on her life, now at 39, with a positive viewpoint. This melancholic outlook is displayed during the second stanza, an example being when Walker says, ââ¬Å"I learned to see bits of paper as a way to escape the life he knew.â⬠This shows that the personaââ¬â¢s father exposed her to the importance of money as a young child. The quote also implies that as he was in a direRead MoreFreuds Theories on Personality Development Essay555 Words à |à 3 Pagesthree different parts of the mind, which are based on our level of awareness; conscious, preconscious, and subconscious mind. The conscious mind is where we are currently in focus of attention at the moment. The preconscious consists of things which we are aware, but we are not paying our full attention. These thoughts can easily be brought into the conscious mind if chosen to do so. It is possible to control our awareness to a certain extent. The subconscious level Read MoreAfter The First Two Weeks Of Class, A First Year Teacher1262 Words à |à 6 Pagesefficient method to help her student. Incorporating art-based interventions effectively developed coping skills, self-expression, open communication, spirituality, and began the healing process for children who have experienced trauma. Aftermath of Childhood Trauma Children who have experienced trauma demonstrated various symptoms and reactions, and found it difficult to express themselves or verbalize events. Traumatic events encompassed both the body and mind with the power to overwhelm ordinary humanRead MoreChildhood Memory758 Words à |à 4 PagesChildhood Memory On June 8th, 1990 is when I entered this place that we call Earth. Born to Montasser and Nagla Hassan, the only girl and the youngest with two older brothers, nine and seven years apart. My parents were born and raised in Cairo, Egypt, and moved to America after getting married, leaving their families behind to better their future and the lives of their future off springs. Their courage and dedication to life and each other is a characteristic that they carried on throughout theirRead MoreBattles in the Desert Essay634 Words à |à 3 PagesCarlos encounter social and political changes. Carlos narrates his own experiences during his childhood when social and political problems are happening. The time period is during the regime of the government of Miguel Aleman. Carlosââ¬â¢ experiences demonstrate the changes of his own personal life, and the impact of the American culture on Mexico. I believe Carlos is reflecting his personal childhood lived at Mà ©xico, and also the unwil ling changes of his personality. How Carlos enjoys a momentRead MoreEssay about Gender differences and autobiographical memories1599 Words à |à 7 Pagesï » ¿ Autobiographical memory is essentially a system that contains episodic memories from individualsââ¬â¢ lives, autobiographical memory is what makes each and every one of us different to another, and essentially what forms the self, connecting us to others, history and the future. ââ¬Å"Autobiographical memories from the mundane to the profound, help form the self, they provide personal historical context or personal biography for who we are now: they are in essence a ââ¬Ëdatabaseââ¬â¢ of the self.â⬠(Conway
Deception Point Page 72 Free Essays
The President looked around the room for Tench. He had not seen her since before his press conference, and she was not here now. Odd, he thought. We will write a custom essay sample on Deception Point Page 72 or any similar topic only for you Order Now This is her celebration as much as it is mine. The news report on television was wrapping up, outlining yet again the White Houseââ¬â¢s quantum political leap forward and Senator Sextonââ¬â¢s disastrous slide. What a difference a day makes, the President thought. In politics, your world can change in an instant. By dawn he would realize just how true those words could be. 85 Pickering could be a problem, Tench had said. Administrator Ekstrom was too preoccupied with this new information to notice that the storm outside the habisphere was raging harder now. The howling cables had increased in pitch, and the NASA staff was nervously milling and chatting rather than going to sleep. Ekstromââ¬â¢s thoughts were lost in a different storm-an explosive tempest brewing back in Washington. The last few hours had brought many problems, all of which Ekstrom was trying to deal with. And yet one problem now loomed larger than all the others combined. Pickering could be a problem. Ekstrom could think of no one on earth against whom heââ¬â¢d less rather match wits than William Pickering. Pickering had ridden Ekstrom and NASA for years now, trying to control privacy policy, lobbying for different mission priorities, and railing against NASAââ¬â¢s escalating failure ratio. Pickeringââ¬â¢s disgust with NASA, Ekstrom knew, went far deeper than the recent loss of his billion-dollar NRO SIGINT satellite in a NASA launchpad explosion, or the NASA security leaks, or the battle over recruiting key aerospace personnel. Pickeringââ¬â¢s grievances against NASA were an ongoing drama of disillusionment and resentment. NASAââ¬â¢s X-33 space plane, which was supposed to be the shuttle replacement, had run five years overdue, meaning dozens of NRO satellite maintenance and launch programs were scrapped or put on hold. Recently, Pickeringââ¬â¢s rage over the X-33 reached a fever pitch when he discovered NASA had canceled the project entirely, swallowing an estimated $900 million loss. Ekstrom arrived at his office, pulled the curtain aside, and entered. Sitting down at his desk he put his head in his hands. He had some decisions to make. What had started as a wonderful day was becoming a nightmare unraveling around him. He tried to put himself in the mindset of William Pickering. What would the man do next? Someone as intelligent as Pickering had to see the importance of this NASA discovery. He had to forgive certain choices made in desperation. He had to see the irreversible damage that would be done by polluting this moment of triumph. What would Pickering do with the information he had? Would he let it ride, or would he make NASA pay for their shortcomings? Ekstrom scowled, having little doubt which it would be. After all, William Pickering had deeper issues with NASAâ⬠¦ an ancient personal bitterness that went far deeper than politics. 86 Rachel was quiet now, staring blankly at the cabin of the G4 as the plane headed south along the Canadian coastline of the Gulf of St. Lawrence. Tolland sat nearby, talking to Corky. Despite the majority of evidence suggesting the meteorite was authentic, Corkyââ¬â¢s admission that the nickel content was ââ¬Å"outside the preestablished midrange valuesâ⬠had served to rekindle Rachelââ¬â¢s initial suspicion. Secretly planting a meteorite beneath the ice only made sense as part of a brilliantly conceived fraud. Nonetheless, the remaining scientific evidence pointed toward the meteoriteââ¬â¢s validity. Rachel turned from the window, glancing down at the disk-shaped meteorite sample in her hand. The tiny chondrules shimmered. Tolland and Corky had been discussing these metallic chondrules for some time now, talking in scientific terms well over Rachelââ¬â¢s head-equilibrated olivine levels, metastable glass matrices, and metamorphic rehomogenation. Nonetheless, the upshot was clear: Corky and Tolland were in agreement that the chondrules were decidedly meteoric. No fudging of that data. Rachel rotated the disk-shaped specimen in her hand, running a finger over the rim where part of the fusion crust was visible. The charring looked relatively fresh-certainly not three hundred years old-although Corky had explained that the meteorite had been hermetically sealed in ice and avoided atmospheric erosion. This seemed logical. Rachel had seen programs on television where human remains were dug from the ice after four thousand years and the personââ¬â¢s skin looked almost perfect. As she studied the fusion crust, an odd thought occurred to her-an obvious piece of data had been omitted. Rachel wondered if it had simply been an oversight in all the data that was thrown at her or did someone simply forget to mention it. She turned suddenly to Corky. ââ¬Å"Did anyone date the fusion crust?â⬠Corky glanced over, looking confused. ââ¬Å"What?â⬠ââ¬Å"Did anyone date the burn. That is, do we know for a fact that the burn on the rock occurred at exactly the time of the Jungersol Fall?â⬠ââ¬Å"Sorry,â⬠Corky said, ââ¬Å"thatââ¬â¢s impossible to date. Oxidation resets all the necessary isotopic markers. Besides, radioisotope decay rates are too slow to measure anything under five hundred years.â⬠Rachel considered that a moment, understanding now why the burn date was not part of the data. ââ¬Å"So, as far as we know, this rock could have been burned in the Middle Ages or last weekend, right?â⬠Tolland chuckled. ââ¬Å"Nobody said science had all the answers.â⬠Rachel let her mind wander aloud. ââ¬Å"A fusion crust is essentially just a severe burn. Technically speaking, the burn on this rock could have happened at any time in the past half century, in any number of different ways.â⬠ââ¬Å"Wrong,â⬠Corky said. ââ¬Å"Burned in any number of different ways? No. Burned in one way. Falling through the atmosphere.â⬠ââ¬Å"Thereââ¬â¢s no other possibility? How about in a furnace?â⬠ââ¬Å"A furnace?â⬠Corky said. ââ¬Å"These samples were examined under an electron microscope. Even the cleanest furnace on earth would have left fuel residue all over the stone-nuclear, chemical, fossil fuel. Forget it. And how about the striations from streaking through the atmosphere? You wouldnââ¬â¢t get those in a furnace.â⬠Rachel had forgotten about the orientation striations on the meteorite. It did indeed appear to have fallen through the air. ââ¬Å"How about a volcano?â⬠she ventured. ââ¬Å"Ejecta thrown violently from an eruption?â⬠Corky shook his head. ââ¬Å"The burn is far too clean.â⬠Rachel glanced at Tolland. The oceanographer nodded. ââ¬Å"Sorry, Iââ¬â¢ve had some experience with volcanoes, both above and below water. Corkyââ¬â¢s right. Volcanic ejecta is penetrated by dozens of toxins-carbon dioxide, sulfur dioxide, hydrogen sulfide, hydrochloric acid-all of which would have been detected in our electronic scans. That fusion crust, whether we like it or not, is the result of a clean atmospheric friction burn.â⬠Rachel sighed, looking back out the window. A clean burn. The phrase stuck with her. She turned back to Tolland. ââ¬Å"What do you mean by a clean burn?â⬠He shrugged. ââ¬Å"Simply that under an electron microscope, we see no remnants of fuel elements, so we know heating was caused by kinetic energy and friction, rather than chemical or nuclear ingredients.â⬠ââ¬Å"If you didnââ¬â¢t find any foreign fuel elements, what did you find? Specifically, what was the composition of the fusion crust?â⬠ââ¬Å"We found,â⬠Corky said, ââ¬Å"exactly what we expected to find. Pure atmospheric elements. Nitrogen, oxygen, hydrogen. No petroleums. No sulfurs. No volcanic acids. Nothing peculiar. All the stuff we see when meteorites fall through the atmosphere.â⬠Rachel leaned back in her seat, her thoughts focusing now. How to cite Deception Point Page 72, Essay examples
Do People Have The Right To Choose free essay sample
When Essay, Research Paper Hickey 1 What precisely is euthanasia? There are many signifiers of this pattern, including physician assisted sucide, active mercy killing, and inactive mercy killing. In one commendation, mercy killing is the pattern of stoping a individuals life. Euthanasia is practiced worldwide be it legitimate or extremely illegal. Along with our apprehension and acception of mercy killing in todays # 8217 ; society, comes the unreciprocated inquiry, do people have the right to take when to decease? Euthanasia, besides known as clemency violent death, is the pattern of stoping life in order to give release from incurable agony or disease. The word comes form the Hellenic for an easy decease. Euthanasia, technically, refers to assisting patients end their ain lives and does non use to halting life prolonging interventions such as inhalators, or a bash non revive order. ( Glossary # 8230 ; ) Euthanasia can be active or inactive. Active mercy killing agencies that a doctor or other individuals involved with the attention of a patient, takes a calculated action to kill. We will write a custom essay sample on Do People Have The Right To Choose or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Administering an overdose of any prescribed drug is considered active mercy killing. Passive mercy killing agencies allowing a patient dice by manner of the deficiency of intervention, or suspending intervention that has begun. Examples of passive mercy killing include taking patients off a inhalator or taking other life-support systems. Stoping the nutrient Hickey 2 supply, normally occurs in the aged with intavenous devices. ( International # 8230 ; ) A great trade of the contention environing mercy killing comes from the determination procedure. Who decides if a patient is to decease? This issue has non been established lawfully in the United States. The affair is left to province jurisprudence, which normally allows the doctor in charge to propose the option of decease to a patients relatives, particularly if the patient is encephalon dead. ( Euthanasia # 8230 ; ) In an effort to do determinations about when their ain lives should stop, several terminally sick patients in the early 1990 # 8217 ; s used a controversial self-destruction device, developed by Dr. Jack Kevorkian, to stop their lives. This device was created from bit aluminium, a plaything auto, and other garbages scavenged from garage gross revenues and flea markets. The device consisted of a needle which was inserted into the arm of the patient get downing the endovenous flow of a toxicant solution. Kevorkian subsequently switched to a more luxuriant machine which consisted of a tightly fitted mask placed over the face, conncected to a C monoxide case shot. Kevorkian has been involved in 27 deceases to day of the month and has neer been convicted of any incorrect making. ( The Real # 8230 ; ) In parts of Europe, the determination devising procedure has go really flexible. Even in instances where the patients are Hickey 3 non encephalon dead, patients have been put to decease without their consent, at the petition of relations, or at the insisting of doctors. Many instances of nonvoluntary mercy killing affect older people or newborn babies. This is believed to be caused by the # 8220 ; non worthy of life # 8221 ; construct practiced in Nazi Germany ( 1933-45 ) . ( Nazism ) In states where nonvoluntary mercy killing is non legal, the tribunal systems have proven to be really indulgent in covering with medical personel who pattern it. In the Neatherlands and Japan, for illustration, if doctors follow certain guidlines they may transport out mercy violent deaths on terminally sick people. Courts have besides proven to be slightly indulgent with friends or relations who have assisted terminally ill patients to decease. ( Flynn 1-2 ) Euthanasia may look like a dignified manner of death, and in one commendation is described as painlessly seting to decease people who have incurable, painful, or straitening dieseases or disablements. This definition has proven false nevertheless. When a individual is killed with drugs ( deadly injection ) there organic structure frequently has violent paroxysms and musculus cramps. This is by no means a peaceable or dignified manner of deceasing. Besides, if a patient is non killed by the drugs administered to them, so they are frequently times suffocated with a plastic bag by the go toing doctor. ( International Anti # 8230 ; ) Hickey 4 Many physicians are opposed to the legilization of mercy killing. They believe that it is contrary to the full Hippocratic Oath which states, # 8220 ; # 8230 ; I will follow that system of regimen which, harmonizing to my ability and judgement, I see for the benefit of my patients # 8230 ; I will give no lifelessly medical specialty to any one if asked, nor suggest any such advocate # 8230 ; # 8221 ; One doctor provinces, # 8220 ; It ( mercy killing ) would gnaw trust between terminally sick patients and their physicians. # 8221 ; He farther goes on to province that, # 8220 ; Alternatively of therapists, physicians would go traders in decease # 8230 ; As a physician, I would non desire the province stating me to make away with somebody. # 8221 ; ( Risley 1-2 ) Mercy violent death is lawfully considered slaying in the United States, whether it involves shooting person with a drug to # 8220 ; hasten decease # 8221 ; or striping the individual of foods necessary to maintain him or her alive. But most provinces including Iowa, now have Torahs allowing # 8220 ; drawing the stopper # 8221 ; on person who has signed a papers stating he or she does non desire life prolonged by unreal agencies. This papers is called a bash non revive order. The papers provinces if a patients # 8217 ; bosom stops whipping, cardiorespiratory resuscitation will non be performed to protract life. ( Can We # 8230 ; ) Oregon has a # 8220 ; Death With Dignity Act # 8221 ; which states, # 8220 ; An Hickey 5 grownup who is capable and a occupant of Oregon may originate a written petition for medicine. The individual must be declared terminally ill by an go toing doctor. The individual must besides me declared terminally ill by a consultin doctor. The individual must recieve guidance to be certain of mental compitence. The go toing physician must inquire the patient to notify next of family. The individuals # 8217 ; medical records must be exhaustively reviewed. # 8221 ; This helps to do certain that all participants of this plan are sound of head and terminally ill. ( The Oregon # 8230 ; ) Euthanasia is explicitly criminalized in 35 provinces. Nine provinces criminalize assisted sucicide through common jurisprudence. ( Alabama, Idaho, Maryland, Massachusetts, Michigan, Nevada, South Carolina, Vermont, West Virginia ) Three provinces have abolished the common jurisprudence of offenses and do non hold legislative acts criminalizing aided self-destruction. ( North Carolina, Utah, Wyoming ) In Ohio, that province # 8217 ; s supreme tribunal ruled that aided self-destruction is non a offense. Merely the province of Oregon licenses doctor assisted suicide. If a doctor is convicted of any incorrect making in relation to the decease of a patient which is lawfully, ethically, or morally incorrect they may hold there liscense to pattern medical specialty revoked. ( Assisted suicide # 8230 ; )
Monday, May 4, 2020
Pharmaceutical Isolator Mode of Operation
Question: Describe about the Pharmaceutical Isolator for Mode of Operation. Answer: Design and operation of Isolator Systems: Isolators are designed to provide continuous and total isolation of the internal area of the isolator form the external environment. Following are the design considerations for the isolators : size, materials, mode of operation (manual or automatic), ergonomic mock up, material compatibility with the product to be sterilized, type of air flow (laminar or turbulent), control systems for the operation, transferability of equipment and type of products (tested or produced). Isolators are also designed to separate internal area from its operators also. Isolators work on the principle of the positive pressure. Full wall and considerable overpressure is useful in the physical and aerodynamic separation of the separation of the internal components form the external environment. There are two types of designs of isolator are available like closed and open operation. Isolators with closed design use aseptic connection to transfer material to auxiliary equipment. Isolators with closed design r emain closed during its operation. Isolators with open design possess openings for the ingress or outgress of the material. These openings are specifically designed using continuous overpressure to avoid entry of contamination inside the isolator chamber. Isolators with positive pressure design are being widely used and isolators with negative pressure design are being used for handling toxic products. Designs of the isolators with negative pressure are complicated because these types of isolators should satisfy two objectives. These objectives are sterility of the drugs inside the isolator and protection of the operator form the toxic material inside the isolator. Isolators with negative pressure are designed to have special buffer zone. This buffer zone can be used as exhaust for both incoming air in the room and outgoing positive pressure air. By virtue of this, sterile product gets protection from the contaminated air (Midcalf, 2004; Agalloco and Akers, 2016). Advantages: Advantages of the isolator system include: capability to sustain sterility of the equipment for considerably longer duration of time, isolator system is comparatively less expensive in terms of operation cost as compared to the other system like clean room, there are very less chances of sterility false positives due to use of isolator system and there is no requirement of gowning to the operator while using isolator system. Operating cost of isolator is lower as compared to the nonbarrier system. Isolators produce less environmental contamination as compared to the traditional cleanroom. Speed of air and exchange of air is also less in isolator as compared to the traditional cleanroom. This helps isolators in producing less environmental contamination as compared to the cleanroom. In terms of biodecontamination also, isolator has more advantage as compared to the cleanroom. In isolator, only drug and excipients used for the manufacturing comes in direct contact with the operating sy stem. On the other hand, in case of cleanroom human intervention is more in operating system Disadvantages: These isolators have higher capital cost as compared to the non-barrier systems. Time for the qualification of isolators is more as compared to the conventional cleanrooms. It reflects, there is need of additional requirements for qualification of isolator and there is no technical hurdle in its qualification. Isolators have limited flexibility and for its installation there is requirement of significant planning (Agalloco and Carleton, 2007; Coles, 2004). Sterilization processes and its recommendations: Different methods of sterilization used in pharmaceutical industry are dry heat sterilization, chemical sterilization, radiation sterilization and filtration sterilization. Dry heat sterilization kills microorganisms by denaturing proteins and nucleic acids. This dry heat sterilization is simple and cost effective method of sterilization of pharmaceutical products. This method can be useful for the sterilization of glasswares, non-aqueous thermostable liquids and thermostable powders. In radiation sterilization, ionizing and non-ionizing radiation like gamma and X rays can be used. These radiations create free hydrogen radicals, hydroxyl radicals and peroxide radicals which cause intracellular damage to microorganisms and kill them. UV radiation has the capacity to reduce airborne contamination in room by approximately 90 % during the period of 30 minutes. Pharmaceutical powders are more resistant to degradation by ionizing radiation as compared to the pharmaceutical liquids. Radiati on sterilization can be very useful in the sterilization of the thermolabile products like penicillin, streptomycin, thiamine, and riboflavin. Chemical sterilization incorporates use of exposure of materials to be sterilized to the gases like ethylene oxide, formaldehyde, glutaraldehyde and propylene oxide. Ethylene oxide is the most common sterilizing agent used and it acts by the alkylation. Ethylene oxide approximately takes 2 to 5 h at 55C to complete sterilization process. Ethylene oxide is specifically used for the sterilization of the gloves, plastic syringes and disposable needles. Ethylene oxide can be used to sterilize thermolabile pharmaceutical products like penicillin. However, products like thiamine, streptomycin and riboflavin lose potency upon exposure to the ethylene oxide. Filtration sterilization is widely used method for the sterilization of thermolabile products which gets degraded due to heat exposure of other method of sterilization. Filtration sterilization m ethods dont kill the bacteria but remove the bacteria form the material to be sterilized. In filtration sterilization method, material to be sterilized passed through the sterile filter and immediately transferred to the sterile container. Prefiltration of pharmaceutical products can be performed by depth and surface filtration to remove large particles. Different types of filters can be combined together for the effective sterilization. Filtration sterilization can be effectively utilized for the filtration of ophthalmic solutions and biological products. It can also be used for the sterilization of the air and gases to be supplied to aseptic area. Restricted Access Barriers (RABs) are designed to augment the aseptic operations to be carried out in the clean room. Mobile clean room can be used to carry out aseptic operations with more flexibility in the location (Aulton and Taylor, 2013; Jasti and Ghosh, 2004). Environmental monitoring and integrity testing: There is the provision of both viable and non-viable particle monitoring in the isolator system. Both viable and non-viable particle monitoring are the essential components of the isolator. These are not essential components of the sterility test isolator, however it is getting popularity in the recent times. Contamination control can be effectively controlled by the environmental monitoring. Shift of gloves use form the neoprene gloves to the hypalon gloves have dramatically decreased the contamination in case of isolators. In modern isolators, contamination due to gloves is in the same level of the airborne contamination recovery which is a measure of environmental monitoring. As there is very low level of contamination in isolators, intensity of environmental monitoring is very high. For finding small quantity, it is mandatory to evaluate more precisely. Due to difficulty in measurement of zero contamination and due to limitations of limit of detection (LOD), it is difficult to pe rform environmental monitoring in isolators. Isolator environment is extremely clean and there is possibility of getting contamination in not more than 10000 samples. It is not perfect to say isolators are sterile but these are safe enough. Approximately 1 ml sample is required over a period of four hours for the environmental monitoring in case of isolators. Active air sampling is more suitable as compared to the settle plates for environmental monitoring in case of isolators. Surface samples decontaminated with the Vapor-Phase Hydrogen Peroxide are not suitable because these samples are not going to give any type of results. Physical measures like air filtration system and pressure differentials are more valuable as compared to the evaluation of microbial contamination. Isolator performance can be more effectively monitored by evaluating total particulate count as compared to the microbial contamination. Environmental monitoring doesnt give exact data for the sterility. There is e xistence of pathogens which cant be detected by the environmental monitoring. Few pathogens exist in the environment, which are viable but cant be culturable. It reflects, these pathogens have metabolic activity but difficult to culture them (Agalloco and Akers, 2006; Katayama et al., 2008). References: Agalloco, J., and Akers, J. (2016). Advanced Aseptic Processing Technology. CRC Press. Agalloco, J. P., and Carleton, F. J. (2007). Validation of Pharmaceutical Processes. CRC Press. Agalloco, J., and Akers, J. (2006). Simplified Risk Analysis for Aseptic Processing: The Akers-Agalloco Method. Pharmaceutical Technology, 30(7), pp. 60-76. Aulton, M.E. and Taylor, K. M.G. (2013). Aulton's Pharmaceutics: The Design and Manufacture of Medicines. CRC Press LLC. Coles, T. (2004). Isolation Technology: A Practical Guide. CRC Press. Jasti, B. R. and Ghosh, T. K. (2004). Theory and Practice of Contemporary Pharmaceutics. CRC Press. Katayama, H., et al., (2008). Proposal for a New Categorization of Aseptic Processing Facilities Based on Risk Assessment Scores. PDA Journal of Pharmaceutical Science and Technology, 62(4), pp. 235-243. Midcalf, B. (2004). Pharmaceutical Isolators: A Guide to Their Application, Design and Control. Pharmaceutical Press.
Tuesday, April 14, 2020
College Composition Sample Essay - How to Write Excellent One
College Composition Sample Essay - How to Write Excellent OneThere are many reasons that students will find themselves using a college composition sample essay. The most common reason is to show how they came up with the idea for the essay. They want to prove that they have a great writing ability and that they really believe what they have written. A lot of students are afraid to ask for help, which is understandable since the teachers probably would have given them a big grade if they asked.However, not every student has had any exposure to writing and good high school writing. If you have not had any experience in writing, it would be very beneficial to get some practice writing a college composition sample essay. You can find some help from the college you attend, but it would be wise to do some research before selecting one. This is because not all colleges are alike when it comes to how they grade.Some colleges have different types of writing courses. Some are taught by experie nced professionals and some are taught by beginners. This is another way that the school can change the style of the writing course. It is also beneficial to find out whether the writing course has weekly lessons or just on a regular basis.You should also use the services of a good tutor. This is an excellent way to learn how to properly use English and the grammatical structure of the language. It would be a good idea to do some research to find out what other students are saying about their tutors. This will help you determine whether you need help with your writing or not.If you have already begun to write a college composition sample essay, try to use it as a blueprint to write a better one. This is the best way to improve the quality of your work. It would be a good idea to ask the professor what types of topics he wants to teach his students. This will give you some ideas about topics to use in your essay.It is also important to write a good essay. Use proper grammar and punct uation, and always finish the sentence in a polite manner. Do not forget to put references back to the original source. This is a form of proofreading.You can find plenty of samples online. Browse through the website of the college you are attending to get some tips on how to format a college composition sample essay. There are lots of websites that offer good information on this topic, so make sure that you take the time to find them.When writing a college composition sample essay, keep in mind that the goal is to write something that your professor would like to read. Never let the theme of the topic overshadow the need to be precise with the spelling and grammar. Try to create a well thought out essay that does not look bad.
Saturday, March 28, 2020
Of Mice and Men Persuasive Essay free essay sample
There is a significant disparity of treatment in the way the criminal justice system handles things. Unfortunately, theres a double standard because there is a double standard in society. â⬠David Raybin. In the novel, Of Mice and Men, by John Steinbeck; Steinbeck introduces two men, George and Lennie, who live in Salinas, California. The novel occurs in the 1930s, during the great depression; in the novel, both men go from one job to another as they try to purchase their own ââ¬ËAmerican Dreamââ¬â¢. The dream to build a shack with an acre of land, but as they struggle with life, their shot at achieving their dream disappears. Towards the end, George murders Lennie in order to solve problems that Lennie caused throughout the plot. Lennieââ¬â¢s murder is categorized as mercy killing; mercy killing is known as killing a person for the benefit of their own good. This novel makes it clear that mercy is the best way to kill people with disabilities, it takes the cruelty out of killing by making it more kind. We will write a custom essay sample on Of Mice and Men Persuasive Essay or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page George committed mercy killing by shooting Lennie. Even though George did not feel right in killing his only best friend, he realized that his actions were justified because Lennie was going to die regardless. In the novel, Lennie is known for killing little creatures on accident, the fact that he kills them by showing love and care towards the animal foreshadows the murder of Curleyââ¬â¢s wife. Lennie accidently killed Curleyââ¬â¢s wife by petting her hair, when George realizes what Lennie has done he realizes that he has to kill Lennie before Curley or the police. It is because of Lennieââ¬â¢s incapacities that allow mercy killing to be better then capital punishment, since Lennie does not understand the difference from right and wrong. It is for the best to kill someone out of mercy, and put them out of their misery, than to do capital punishment which beats and tortures them to death. Mercy killing may sound like a dreadful thing to do, but would you rather see a loved one suffering, and in misery, or would you rather see them finally resting and happily at peace? For example, compare Candyââ¬â¢s dog and Lennie. Candyââ¬â¢s dog was already dying slowly; the dog was old, blind and miserable. ââ¬Å"Iââ¬â¢ll put the old devil out of his misery right now and get it over with. Ainââ¬â¢t nothing left for him. Canââ¬â¢t eat, canââ¬â¢t see, canââ¬â¢t even walk without hurtinââ¬â¢,â⬠says Carlson, a character from the novel that realizes that the dog would be better off by dying then living another painful day. Lennie like the dog would have been tortured or beaten to death once Curley discovered who killed his wife. Capital punishment is necessary depending on the situation, but mercy killing is the best when it came to people or animals with incapacities. Mercy killing is killing out of love; it takes love and courage to know that an animal or a friend like Lennie is better off dead. George killed his best friend out of love; he loved Lennie so much that he rather kill Lennie himself then to have Curley kill Lennie out of spite.
Saturday, March 7, 2020
Corporate Takeover Essay Example
Corporate Takeover Essay Example Corporate Takeover Essay Corporate Takeover Essay Aurielle Cummings Business Policy November 10, 2010 Anatomy of a Corporate Takeover What did you think of this video? I think this video is a very informative series addressing ethical situations and dilemmas. As a business major it is very important to understand the challenging issues you will be faced with as you embark on the career path into corporate America. The video examines ethical conflicts and gives students a background the tradition of ethics. When there is always so much being said and written about the decline of ethical behavior in our country, a series like this was a appropriate effort to alleviate confusion over what we have a right to do and what is the right thing to do. What questions are being addressed? Some of the questions being addressed are whose best economic interests are most important? Does the government have a role to play in this game of high finance? Also, with large amounts of money changing hands, what ethical concerns surround this issue? While consumers and producers in the world make most decisions that mold the economy, government activities have a powerful effect on the U. S economy. The federal government controls the general pace of monetary activity, attempting to preserve steady growth, high levels of employment, and price stability. By changing spending and tax rates or running the money supply and maintaining the use of credit, it can slow down or speed up the economys rate of growth. As a result, it affects the level of prices and employment. With the rising focus on globalization of the financial system, ethical issues are often submerged by the objective of increasing success. Ethics covers an extensive area in terms of business. Moral principles that one follows should please the customer, the employee, and the employer. There are values that should be satisfied within the organization as well. I believe most ethical issues begin the management stage of the organization. In todayââ¬â¢s environment, managers can have a great deal of effect on an employeeââ¬â¢s ability to move up in a company. As a worker of a company, management teams also have managers to get reports. It is important for managers to not only have lack of prejudice for their employees, but to achieve somewhat in business, they require to be competent to handle be capable to supervise all of their work associations. In the midst of making money in a business any organization should have an effective leader. Why is this video important now after 30 years? In business all ethics are determined and displayed by the leadership. The leaders of an organization or company must be determined to follow, a personal and business code of ethics. As a whole I believe we learn from examples, not by from what people tell us to do. The importance of ethics in business is that it sets the tone for a businessââ¬â¢s success or failure. Ethical conduct is a very private matter, which requires that a person be honest and truthful in all business dealings. Since ethical behavior is so personal, it is unlikely to be given any acknowledgment. While there are many awards for corporate social responsibility, awards that recognize ethical behavior are rare. A well-communicated dedication to ethics sends a influential message that moral behavior is measured to be business essential. Companies, led by top management, are increasingly adopting ethical codes of conduct. As ethical performance comes to the forefront, more and more companies will be taking steps to make certain that the ethics of their corporation and its employees are unquestionable. What are your views on stakeholder vs shareholder rights? Explain. A stakeholder is a person who has or shares an interest in a business project. There are primary, key, and secondary stakeholders who can be positively or negatively impacted by, or cause an impact on the dealings of a company, government or organization. The goal of a stakeholder and the project team is to assure successful outcomes for the project. Stakeholder analysis needs to be performed at the start of new projects, and it is important to identify all stakeholders. A shareholder on the other hand is any person, company, or institution that owns at least one share in a company. Stakeholders and shareholders have different value perspectives as discussed in the video. The shareholder value perspective emphasizes profitability over responsibility. Also, shareholder value believes success can be measured by things such as share price, dividends, and economic profit. Social responsibility is also not a matter, and claims that society is best served by organizations pursuing self-interest and economic competence. The stakeholder value perspective emphasizes the exact opposite which is responsibility over profitability. Stakeholder values suggest that an organizations success should be measure by the satisfaction among all stakeholders. With stakeholder rights social responsibility is an organizational matter and claims that society is best served by pursuing joint interests and economic symbiosis. I agree with the stakeholder values because this economy shouldnââ¬â¢t be based on just one personââ¬â¢s view over things. Social responsibility is a huge part of our economy as whole, and if responsibility was taken for some of the actions taken in previous years, a lot of the same mistakes wouldnââ¬â¢t have been made twice. In business practices we have a ethical responsibility to act in good faith, and in most cases where a large amount of money is changing hands there are large ethical concerns as stated in the video. I believe all money isnââ¬â¢t good money, and to be a successful business you do want to be profitable, but not by gaining it in an unethical sense, or by ignoring the responsibilities you are given as an owner.
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