Sunday, May 24, 2020

What Makes Someone a Successful Entrepreneur - 1623 Words

Mind Your Own Business What makes someone a successful entrepreneur? It certainly helps to have strong technology skills or expertise in a key area, but these are not defining characteristics of entrepreneurship. Instead, the key qualities are traits such as creativity, the ability to keep going in the face of hardship, and the social skills needed to build great teams. If you want to start a business, it s essential to learn the specific skills that underpin these qualities. It s also important to develop entrepreneurial skills if you re in a job role where you re expected to develop a business, or take things forward more generally. It s very easy to get lost trying to rate ourselves against our†¦show more content†¦Optimism: Are you an optimistic thinker? Optimism is truly an asset, and it will help get you through the tough times that many entrepreneurs experience as they find a business model that works for them. Vision: Can you easily see where things can be improved? Can you quickly grasp t he big picture, and explain this to others? And can you create a compelling vision of the future, and then inspire other people to engage with that vision? Initiative: Do you have initiative, and instinctively start problem-solving or business improvement projects? Desire for Control: Do you enjoy being in charge and making decisions? Are you motivated to lead others? Drive and Persistence: Are you self-motivated and energetic? And are you prepared to work hard, for a very long time, to realize your goals? Risk Tolerance: Are you able to take risks, and make decisions when facts are uncertain? Resilience: Are you resilient, so that you can pick yourself up when things don t go as planned? And do you learn and grow from your mistakes and failures? Interpersonal Skills As a successful entrepreneur, you ll have to work closely with people - this is where it is critical to be able to build great relationships with your team, customers, suppliers, shareholders, investors, and more. Some people are more gifted in this area than others, but, fortunately, you can learn and improve these skills. The types of interpersonal skills you ll needShow MoreRelatedCharacteristics of Successful Entrepreneurs1015 Words   |  5 PagesCharacteristics of successful entrepreneurs An entrepreneur is someone with the capacity to lead a business to success and is willing to take the risks in order to accomplish their goals. (Dollonger, 2002). Starting a new business is an example of entrepreneurship. Entrepreneurs are very important in order for any business to succeed, however, only some entrepreneurs will succeed in life. Here are some of the characteristics of successful entrepreneurs. Passion Most successful entrepreneurs are have a passionRead MoreBeing an Entrepeneur1043 Words   |  4 Pagesgreat entrepreneur who wanted to make his business successful. An entrepreneur needs a variety of skills but does not need to have a formal education. Being an entrepreneur is challenging even if an individual is well educated on the field or has no education at all. There is always the risk conducting business because of the competition with other companies. However, what does an entrepreneur do? Do you have what it takes to be on top the business world and compete ? An entrepreneur must haveRead MorePolitical And Present Day Entrepreneurs928 Words   |  4 PagesIn this paper we examine economical, political and present day entrepreneurs. Outline a politico-economic growth system centered on the entrepreneurs. This examination is presented to discuss the challenges a modern day entrepreneur’s face in the ultra-competitive technology market place. We also point to a modern day entrepreneur who succeeded in a very stereotypical industry. Gender stereotypes are also of immense concern, and presented for reader awareness. The pitfalls associated with a techRead MoreEntrepreneur Characteristics1725 Words   |  7 Pagesto Be a Successful Entrepreneur? ABSTRACT First, there was an interview with a successful entrepreneur. Second, there was a talk on entrepreneurship by a guest speaker, Mr. Azmi Ahmad (the CEO of Skali.com) and later, an elevator speech by fellow students on various issues related to entrepreneurship. This collective information and some reading on entrepreneurship journals, books and articles have brought to the idea on writing this paper, towards certain perspective, on successful entrepreneurialRead MoreCharacteristics of a Successful Entrepreneur Essay1598 Words   |  7 PagesCharacteristics of a Successful Entrepreneur ABSTRACT First, there was an interview with a successful entrepreneur. Second, there was a talk on entrepreneurship by a guest speaker, Mr. Azmi Ahmad (the CEO of Skali.com) and later, an elevator speech by fellow students on various issues related to entrepreneurship. This collective information and some reading on entrepreneurship journals, books and articles have brought to the idea on writing this paper, towards certain perspective, on successful entrepreneurialRead MoreEntrepreneurship Is Not Only A Word Entrepreneur1349 Words   |  6 Pagesthirteenth-century, entreprendre, a French verb originated to mean â€Å"to do something† or â€Å"to undertake.† By the sixteenth century the word, entrepreneur formed. The word entrepreneur refers to someone who undertakes a business venture. An entrepreneur is someone that takes risks in developing, managing and organizing a business or enterprise. Every entrepreneur weighs the risks involved against the potential profit to be gaine d. When they think the gain outweighs the risk they take every opportunityRead MoreThe Is Worth A Tinkers Damn Is The History We Make Today1480 Words   |  6 Pagesis the history we make today.† Henry Ford made this statement somewhere along the line of his entrepreneurial adventures. Its great men like him that have truly shown us the success of the entrepreneur and sparked my interest. When writing this paper I had two specific goals. First to define what an entrepreneur is by defining what an entrepreneur is; in addition, outlining the types and common characteristics. Second is to allow you the reader to grasp an understanding of what attracts such a crowdRead More7 Things Confident Entrepreneurs Never Do1190 Words   |  5 Pagesself-proclaimed entrepreneur and marketer and VP of Marketing at When I Work, wrote an article for Entrepreneur.com titled â€Å"7 Things Confident Entrepreneurs Never Do.† While this article is not an exhaustive list of mistakes entrep reneurs can make, it gets the main point across—entrepreneurs need to be confident because self-confidence is key in the decision-making process (Schermerhorn). Patel says they need to be tenacious and determined and have faith in order to be successful, but he points outRead MoreA Brief Note On Guy Kawasaki : The Top 10 Mistakes Of Entrepreneurs945 Words   |  4 PagesAlfred Mercier once said, â€Å"What we learn with pleasure we never forget.† This quote reveals the importance of how learning something we like with pleasure would often teach us something rather than just feeding anything in our mind. Similarly, the video of â€Å"Guy Kawasaki: The Top 10 Mistakes of Entrepreneurs† was a great learning experience for me. Usually, watching a video about business can be boring since there are not fun and exciting videos that can be watched. Instead, after watching this videoRead MoreWhat Makes A Great Leader?1299 Words   |  6 Pagesthe early 1900s. Everyone is entitled to his or her own opinion. Within the choices we make on an everyday basis, it is imperative to use what we know and have gained through social experiences to complete the possibilities of our â€Å"castle in the air†. For this will make and shape our own destiny, to the top of our zenith. Desire, time management, and caution are what make a great leader. An entrepreneur is someone who is innovative, well determined, and hardworking. Even if one may not have all they

Tuesday, May 19, 2020

The Is The Better Vacation Spot Universal Studios Or...

TESL 99 Which is the Better Vacation Spot? Universal Studios or Disneyland? Suppose the following situation. Spring Break is coming, you want to have some entertainment with lots of fun and good souvenirs. Besides, you do not want to return home in a hurry just for cooking dinner. Then you come up with the amusement park, which can fulfill all demands. The next problem is that there are so many amusement parks, which one is better? After excluding some options by factors such as distance, there are only two left, Universal Studios and Disneyland. However, you are facing a dilemma now. Which one will you going to choose? Price is always the first thing you would be concerned when comparing two amusement parks and making a decision. The ticket of Universal Studios is 85 dollars during Spring Break, and there is no difference between adults and children. Disneyland is a little more expensive, because the ticket costs 119 dollars to get a ticket for an adult, and 113 dollars for a child. However, they both have other ticket options. In Universal Studi os, VIP Experience, which is a priority to all the facilities and a right to other special activities such as taking pictures in famous scenes, is another choice of the ticket while the price of VIP is roughly as three times as the regular one. On the other hand, because Disneyland has two parks, Disney Park, and Disney California Adventure Park, Hopper Ticket provided to go within two parks, by adding fifty dollarsShow MoreRelatedDisney: Marketing Analysis6567 Words   |  27 PagesAnalysis 8 The competitive environment 12 Marketing Objectivesn 13 International Operations 17 Conclusion 20 History and Current Situation The Walt Disney Company started off on the dreams of one man, Walt Disney. He started the Walt Disney Studios in 1926 to make animated films for children but was not satisfied with his accomplishments. As his motion pictures and television programs became successful, he felt a desire to branch out. One area that intrigued him was amusement parks. As a fatherRead MoreThe Walt Disney Company Report15335 Words   |  62 Pagesvehemently and reaffirmed it peak position. The stock prices have skyrocketed, dividends have increased by more than 100% and it seems no looking back for Disney. Here is a caveat, Disney is backing all its future rise on the success of Shanghai Disneyland and acceptance of Star Wars by a very loyal fan base. What if these two aces fail to fire for Disney? Will it still be able to recover and sustain its position on top? Only time will tell if this meteoric rise doesn t become a meteoric fall. Read MoreHk Disney16299 Words   |  66 PagesI. Executive Summary This marketing service plan on Hong Kong Disneyland aims to give concrete recommendations for the improvement of the theme park’s service marketing mix elements or 8Ps. Other than the different recommendations, this paper also contains various information regarding Hong Kong Disneyland’s current situation as well as other related vital knowledge needed for the service plan, such as; Industry Analysis, Competitive Analysis, TOWS analysis and TOWS matrix. The industry analysisRead More Euro Disney Essay6225 Words   |  25 Pagessend his entourage of characters into the real world, through the creation of Disneyland in Anaheim, California. Walt’s Disneyland dream was to create a place where people from all over would be able to go for clean, safe fun, unlike the less-than-wholesome carnivals of the day. He wanted a place that would teach both young and old about America’s heritage and about the diversity of the world. Since July 17, 1955, Disneyland has stood as the icon of Walt’s dream—a park for family-type entertainmentRead MoreResources Capabilities20336 Words   |  82 Pagesthreatened by digital imaging. Over the past 25 years, Kodak has invested billions of dollars developing digital technologies and digital imaging products. Yet proï ¬ ts and market leadership in digital imaging remain elusive for Kodak. Might Kodak have been better off sticking with its chemical know-how and developing its interests in specialty chemicals, pharmaceuticals, and healthcare?7 The difï ¬ culties experienced by established ï ¬ rms in adjusting to technological change within their own markets are well documentedRead MoreUnited Arab of Emirates Country Notebook18844 Words   |  76 Pagesplanned to be six grand projects each of them better than the other. All of the project are designed by the world ´s famoust architects. The Sheikh Zayed National Museum by Foster + Partners The modern art museum Guggenheim Abu Dhabi by Frank Gehry The classical museum Louvre Abu Dhabi by Jean Nouvel The maritime museum by Tadao Ando The Performing Arts Center by Zaha Hadid, and a Biennale Park with 16 pavilions Tashkeel studios in Nad al-Sheba Dubai, a collaborative committedRead MoreUnited Arab of Emirates Country Notebook18844 Words   |  76 Pagesplanned to be six grand projects each of them better than the other. All of the project are designed by the world ´s famoust architects. The Sheikh Zayed National Museum by Foster + Partners The modern art museum Guggenheim Abu Dhabi by Frank Gehry The classical museum Louvre Abu Dhabi by Jean Nouvel The maritime museum by Tadao Ando The Performing Arts Center by Zaha Hadid, and a Biennale Park with 16 pavilions Tashkeel studios in Nad al-Sheba Dubai, a collaborative committedRead MoreMarketing Mistakes and Successes175322 Words   |  702 Pagesmay even be my best book. The new Google and Starbucks cases should arouse keen student interest, and may even inspire another generation of entrepreneurs. A fair number of the older cases have faced significant changes in the last few years, for better or for worse, and these we have captured to add to learning insights. After so many years of investigating mistakes, and more recently successes also, it might seem a challenge to keep these new editions fresh and interesting. The joy of the chaseRead MoreInternational Management67196 Words   |  269 PagesDirector: Paul Ducham Managing Developmental Editor: Laura Hurst Spell Developmental Editor: Jane Beck Associate Marketing Manager: Jaime Halteman Project Manager: Erin Melloy Buyer: Kara Kudronowicz Design Coordinator: Margarite Reynolds Cover Designer: Studio Montage, St. Louis, Missouri Cover Images: Top to bottom,  © Mark Downey/Getty Images; Jacobs Stock Photography/Getty Images;  © Goodshoot/PunchStock Media Project Manager: Balaji Sundararaman Compositor: Aptara ®, Inc. Typeface: 10/12 Times Roman Printer:Read MoreManagement Course: Mba−10 General Management215330 Words   |  862 Pagesthroughout today’s marketplace. Business leaders need to understand that the current marketplace is characterized by the following business truths: ââ€"  ââ€"  ââ€"  ââ€"  The quick and most flexible devour the ponderous and most rigid. Networking and diffusion work better than bureaucracy does. An emphasis on creativity is essential. The people closest to what is happening are those who can lead and improve it the most effectively for a sustained economy. As communication has become increasingly less expensive,

Wednesday, May 13, 2020

The American Civil War The Bloodiest War - 1190 Words

On April 12, 1861 decades of building tensions between the northern and southern United States erupted into the American Civil War. The war began when Confederates attacked Union soldiers at fort Sumter, South Carolina. This happened because the north did not believe in slavery, but the south did. The north went against slavery, but the confederates believed that slavery was good for money because they saved money by not paying the slaves. The election of Abraham Lincoln as president in 1860 caused seven southern states to move from the Union to form the Confederate States of America; four more states joined them after the Civil War began. Some people said that everything leading up to 1860 led to the civil war and everything that happened after it was because of the civil war. The Civil War was also known as The War Between the States. This war was so intense that it put neighbor against neighbor and even sometimes brother against brother. In 1865, when confederates surrendered the Civil War proved to be the bloodiest, costliest (at that time), and most accomplishing war ever fought on our very own soil. Though the Civil war did lead to the death of over 600,000 soldiers, I believe it was worth it. The Civil war is considered the bloodiest war in history because at least 618,000 Americans died in this war, and some experts believe the numbers reached well into the 700,000s. At any number these casualties exceeded the nation’s loss in all its other wars. The battle ofShow MoreRelatedThe Bloodiest Conflict Of The American Civil War1649 Words   |  7 PagesThe bloodiest conflict in American history is the American Civil War. Prior to the war, there were many important events that triggered the conflict between the proslavery forces in the South and antislavery forces in the North. The Missouri Compromise of 1820, the Mexican American War, the Industrial Revolution, the Compromise of 1850, the Abolitionist Movement, the Kansas-Nebraska Act, John Brownâ⠂¬â„¢s Raid on Harper’s Ferry, and the election of Abraham Lincoln were some of the events that contributedRead MoreThe American Civil War : The Bloodiest And Most Gruesome War4070 Words   |  17 PagesIntroduction By all estimation, the American Civil War was considered to be the bloodiest and most gruesome war in American history. There are more US casualties involved in the American Civil War than US casualties in World War I II, Korean, and Vietnam War combined. Historians have discussed possible causes that led to the greatest separation among the American people. It is important to recognize the true causes behind this separation so that history does not repeat itself. It is importantRead MoreThe Civil War Was The Bloodiest War Of American History1759 Words   |  8 Pages The Civil War was the bloodiest war in American history, as the schism between the North and the South turned friends into foes and brothers into sworn enemies. While this war is widely known for the battles that took place upon the land, the United States Navy contributed to the war effort upon the sea and rivers as well. Secretary of the Navy Gideon Welles had three objectives for the Navy during the Civil War and one of them was to blockade the Confederate State of America. The overall goalRead MoreThe Civil War: Bloodiest War in American History Essay782 Words   |  4 Pagesclimax of the bloodiest war in American history, there were two men who had a bond that was much stronger than this all-consuming war. These men had enough faith in each other and in themselves to help them through the war. Both men were fighting for what they solely believed in and even with their different opinions, they still had each other’s back when they didn’t have each other. The fr iendship of Lewis Armistead and Winfield Hancock shows that even one of the strongest forces, war, is still weakerRead MoreEssay about The American Civil War: America’s Bloodiest War716 Words   |  3 PagesThe American Civil War, known as the War Between the States’ by some, was America’s bloodiest war. The Civil War consisted of over 10,000 battles between The Union Army of the North and the South’s Confederate Army, which lasted almost 4 years. The War was fought in 23 states and of the more than 10,000 battles only about 50 were major battles. (Weider, The Civil War, 1) In this paper the reader will learn about important dates of the war also about 4 of the bloodiest battles in the war; the BattleRead MoreThe American Civil War. One Of The Bloodiest And Most Fatal2014 Words   |  9 PagesThe American Civil War One of the bloodiest and most fatal battle in United States History, the American Civil War. The Civil war was a conflict in the nation that the people could never forget. It was a war that costed the lives of the many in the year 1861 to 1865 during the time of the nation’s 16th President, Abraham Lincoln. It was a conflict that arose between dividing states, the Northern free states and Southern slaves states which also referred to as the Union and the Confederate statesRead MoreThe Bloodiest Day On American Soil Since The Civil War1418 Words   |  6 PagesSeptember 11th, 2001 was the bloodiest day on American soil since the Civil War. The United States experienced well planned terrorist attacks on the Twin Towers, Pentagon, and a plane that was headed to Washington D.C, most likely to hit the White House but ended up in a field. A country of nearly three hundred million people nearly came to a pause, meanwhile three thousand people passed away and the nation would be forever changed For some time many people were in shock and afraid to fly. InvestigatorsRead MoreAmerican History: Bloodiest Battle of the Civil War in South Carolina1194 Words   |  5 PagesSouth Carolina was an important key player during the Civil War. South Carolina had major military and political importance throughout the Civil War. South Carolina was the battleground of many significant events during this time. Such as the capture of Port Royal, the Union blockade of Charleston, Shermans march through the state, the burning of Columbia, and Fort Sumter. South Carolina had many important battles fought on its territory, Fort Sumter. Fort Sumter is an island in the CharlestonRead MoreCivil War : A War Between Citizens Of The Same Country1609 Words   |  7 PagesEmma Hart Mrs. Wise History 8Y 11 December 2014 Civil War Civil War is defined as a war between citizens of the same country. Why would America have this fight? The Northern states of America decided that they would no longer tolerate the Southern states treating African Americans as slaves because of the color of their skin. When disputes were brought up over this issue between the North and South, the South was too persistent to have slaves. They worried that the North would be successful inRead MoreA Brief Note On Civil War And Its Effects On The United States1602 Words   |  7 Pages Civil War Civil War is defined as a war between citizens of the same country. Why would America have this fight? The Northern states of America decided that they would no longer tolerate the Southern states treating African Americans as slaves because of the color of their skin. When disputes were brought up over this issue between the North and South, the South was too persistent to have slaves. They worried that the North would be successful in abolishing slavery, so in result, the South went

Wednesday, May 6, 2020

Childhood Memories And Its Effects On Our Lives - 1173 Words

We each have memories, both from long ago and recent times, that we hold dear to us. Memories get us through the hard days and keep us chipper in the good ones. The past is what makes us who we are. It shapes how we act, how we treat others, and simply just what we do on a day to day basis. Memories are the little things that keep this world running smoothly. Imagine what it would be like to lose those memories. What if you were to forget things to the point you were losing your functionality? Every 67 seconds another person in the US falls victim to this disease (www.alz.org). They may remember childhood memories, but forgot where they put the cheese they bought yesterday. As the disease gets worse and worse, they may wander and even forget people they care deeply about and those they interact with daily. Who are these people, and what is the â€Å"it† they are suffering from? These are people suffering from Alzheimers Disease, affecting 5 million individuals in the United States alone. Alzheimers Disease is a type of dementia, a more general term meaning a decline in someone’s mental ability, to the point of affecting their everyday life. Alzheimers is actually the most common form, afflicting about 80% of dementia patients. There are treatments and medications available to help patients with symptoms and slow its progress through the brain, but science has not yet found a way to completely stop it, or even slow it significantly for many patients. As patients continueShow MoreRelatedThe Lifelong Health Effects Of Childhood Trauma1301 Words   |  6 PagesThe topic that I have decided to write about is childhood trauma. I wanted to research the lifelong health effects that are caused by childhood trauma. One thing that has always concerned me is the life of children growing up in war-zones or areas with extreme poverty and crime. I assume that there is a correlation between traumatic experiences and health. Many people would argue that the cor relation behind it is that it is more likely that a person makes bad health decisions like drinking and doingRead MoreIntegrated Analysis Of Service Learning Age Group Late Childhood Essay1368 Words   |  6 PagesIntroduction: Throughout the course of this semester, we discovered the wonders of how the mind and body develop over time. How our brains can grow in knowledge of problem solving skills and how our bodies capabilities decline in older adulthood. In this semester, I focused on one portion of development in particular. I chose to concentrate on late childhood—around ages ten to twelve—because I had no prior knowledge of this age group other than my own personal experiences. My service learning experienceRead MorePoems to Reminisce Childhood1443 Words   |  6 Pagesor reminiscing over it, everyone experiences childhood; the experience elicits a large spectrum of emotions from every reader. The poems ‘Poem at Thirty-Nine’ by Alice Walker, ‘Once Upon a Time’ by Gabriel Okara, and ‘Piano’ by D.H. Lawrence explore the theme of childhood from different perspectives. In ‘Once Upon A Time’, Okara explores childhood as a time of vulnerabil ity, where safety and protection are needed. Walker’s ‘Poem at 39’ views childhood as a time when one can start to progress to theirRead MoreEssay about The Psychodynamic Model of Abnormality1148 Words   |  5 Pagesabnormality but also normality. Freud developed Psychoanalysis. This is a set of techniques for treating the unconscious causes of mental disorders and built up a psychoanalytic theory of how human personality and abnormality develop from childhood. His psychoanalytic approach had a great impact on psychology and psychiatry and was developed by other psychodynamic theorists. Psychoanalysis had a very fixed set of assumptions. One of these is the unconscious processes whereRead MorePoem at 39 by Alice Walker1164 Words   |  5 PagesIn ‘Poem at 39’ by Alice Walker, the persona reminisces over her childhood with a melancholic stance, while still viewing it’s overall impact on her life, now at 39, with a positive viewpoint. This melancholic outlook is displayed during the second stanza, an example being when Walker says, â€Å"I learned to see bits of paper as a way to escape the life he knew.† This shows that the persona’s father exposed her to the importance of money as a young child. The quote also implies that as he was in a direRead MoreFreuds Theories on Personality Development Essay555 Words   |  3 Pagesthree different parts of the mind, which are based on our level of awareness; conscious, preconscious, and subconscious mind. The conscious mind is where we are currently in focus of attention at the moment. The preconscious consists of things which we are aware, but we are not paying our full attention. These thoughts can easily be brought into the conscious mind if chosen to do so. It is possible to control our awareness to a certain extent. The subconscious level Read MoreAfter The First Two Weeks Of Class, A First Year Teacher1262 Words   |  6 Pagesefficient method to help her student. Incorporating art-based interventions effectively developed coping skills, self-expression, open communication, spirituality, and began the healing process for children who have experienced trauma. Aftermath of Childhood Trauma Children who have experienced trauma demonstrated various symptoms and reactions, and found it difficult to express themselves or verbalize events. Traumatic events encompassed both the body and mind with the power to overwhelm ordinary humanRead MoreChildhood Memory758 Words   |  4 PagesChildhood Memory On June 8th, 1990 is when I entered this place that we call Earth. Born to Montasser and Nagla Hassan, the only girl and the youngest with two older brothers, nine and seven years apart. My parents were born and raised in Cairo, Egypt, and moved to America after getting married, leaving their families behind to better their future and the lives of their future off springs. Their courage and dedication to life and each other is a characteristic that they carried on throughout theirRead MoreBattles in the Desert Essay634 Words   |  3 PagesCarlos encounter social and political changes. Carlos narrates his own experiences during his childhood when social and political problems are happening. The time period is during the regime of the government of Miguel Aleman. Carlos’ experiences demonstrate the changes of his own personal life, and the impact of the American culture on Mexico. I believe Carlos is reflecting his personal childhood lived at Mà ©xico, and also the unwil ling changes of his personality. How Carlos enjoys a momentRead MoreEssay about Gender differences and autobiographical memories1599 Words   |  7 Pagesï » ¿ Autobiographical memory is essentially a system that contains episodic memories from individuals’ lives, autobiographical memory is what makes each and every one of us different to another, and essentially what forms the self, connecting us to others, history and the future. â€Å"Autobiographical memories from the mundane to the profound, help form the self, they provide personal historical context or personal biography for who we are now: they are in essence a ‘database’ of the self.†(Conway

Deception Point Page 72 Free Essays

The President looked around the room for Tench. He had not seen her since before his press conference, and she was not here now. Odd, he thought. We will write a custom essay sample on Deception Point Page 72 or any similar topic only for you Order Now This is her celebration as much as it is mine. The news report on television was wrapping up, outlining yet again the White House’s quantum political leap forward and Senator Sexton’s disastrous slide. What a difference a day makes, the President thought. In politics, your world can change in an instant. By dawn he would realize just how true those words could be. 85 Pickering could be a problem, Tench had said. Administrator Ekstrom was too preoccupied with this new information to notice that the storm outside the habisphere was raging harder now. The howling cables had increased in pitch, and the NASA staff was nervously milling and chatting rather than going to sleep. Ekstrom’s thoughts were lost in a different storm-an explosive tempest brewing back in Washington. The last few hours had brought many problems, all of which Ekstrom was trying to deal with. And yet one problem now loomed larger than all the others combined. Pickering could be a problem. Ekstrom could think of no one on earth against whom he’d less rather match wits than William Pickering. Pickering had ridden Ekstrom and NASA for years now, trying to control privacy policy, lobbying for different mission priorities, and railing against NASA’s escalating failure ratio. Pickering’s disgust with NASA, Ekstrom knew, went far deeper than the recent loss of his billion-dollar NRO SIGINT satellite in a NASA launchpad explosion, or the NASA security leaks, or the battle over recruiting key aerospace personnel. Pickering’s grievances against NASA were an ongoing drama of disillusionment and resentment. NASA’s X-33 space plane, which was supposed to be the shuttle replacement, had run five years overdue, meaning dozens of NRO satellite maintenance and launch programs were scrapped or put on hold. Recently, Pickering’s rage over the X-33 reached a fever pitch when he discovered NASA had canceled the project entirely, swallowing an estimated $900 million loss. Ekstrom arrived at his office, pulled the curtain aside, and entered. Sitting down at his desk he put his head in his hands. He had some decisions to make. What had started as a wonderful day was becoming a nightmare unraveling around him. He tried to put himself in the mindset of William Pickering. What would the man do next? Someone as intelligent as Pickering had to see the importance of this NASA discovery. He had to forgive certain choices made in desperation. He had to see the irreversible damage that would be done by polluting this moment of triumph. What would Pickering do with the information he had? Would he let it ride, or would he make NASA pay for their shortcomings? Ekstrom scowled, having little doubt which it would be. After all, William Pickering had deeper issues with NASA†¦ an ancient personal bitterness that went far deeper than politics. 86 Rachel was quiet now, staring blankly at the cabin of the G4 as the plane headed south along the Canadian coastline of the Gulf of St. Lawrence. Tolland sat nearby, talking to Corky. Despite the majority of evidence suggesting the meteorite was authentic, Corky’s admission that the nickel content was â€Å"outside the preestablished midrange values† had served to rekindle Rachel’s initial suspicion. Secretly planting a meteorite beneath the ice only made sense as part of a brilliantly conceived fraud. Nonetheless, the remaining scientific evidence pointed toward the meteorite’s validity. Rachel turned from the window, glancing down at the disk-shaped meteorite sample in her hand. The tiny chondrules shimmered. Tolland and Corky had been discussing these metallic chondrules for some time now, talking in scientific terms well over Rachel’s head-equilibrated olivine levels, metastable glass matrices, and metamorphic rehomogenation. Nonetheless, the upshot was clear: Corky and Tolland were in agreement that the chondrules were decidedly meteoric. No fudging of that data. Rachel rotated the disk-shaped specimen in her hand, running a finger over the rim where part of the fusion crust was visible. The charring looked relatively fresh-certainly not three hundred years old-although Corky had explained that the meteorite had been hermetically sealed in ice and avoided atmospheric erosion. This seemed logical. Rachel had seen programs on television where human remains were dug from the ice after four thousand years and the person’s skin looked almost perfect. As she studied the fusion crust, an odd thought occurred to her-an obvious piece of data had been omitted. Rachel wondered if it had simply been an oversight in all the data that was thrown at her or did someone simply forget to mention it. She turned suddenly to Corky. â€Å"Did anyone date the fusion crust?† Corky glanced over, looking confused. â€Å"What?† â€Å"Did anyone date the burn. That is, do we know for a fact that the burn on the rock occurred at exactly the time of the Jungersol Fall?† â€Å"Sorry,† Corky said, â€Å"that’s impossible to date. Oxidation resets all the necessary isotopic markers. Besides, radioisotope decay rates are too slow to measure anything under five hundred years.† Rachel considered that a moment, understanding now why the burn date was not part of the data. â€Å"So, as far as we know, this rock could have been burned in the Middle Ages or last weekend, right?† Tolland chuckled. â€Å"Nobody said science had all the answers.† Rachel let her mind wander aloud. â€Å"A fusion crust is essentially just a severe burn. Technically speaking, the burn on this rock could have happened at any time in the past half century, in any number of different ways.† â€Å"Wrong,† Corky said. â€Å"Burned in any number of different ways? No. Burned in one way. Falling through the atmosphere.† â€Å"There’s no other possibility? How about in a furnace?† â€Å"A furnace?† Corky said. â€Å"These samples were examined under an electron microscope. Even the cleanest furnace on earth would have left fuel residue all over the stone-nuclear, chemical, fossil fuel. Forget it. And how about the striations from streaking through the atmosphere? You wouldn’t get those in a furnace.† Rachel had forgotten about the orientation striations on the meteorite. It did indeed appear to have fallen through the air. â€Å"How about a volcano?† she ventured. â€Å"Ejecta thrown violently from an eruption?† Corky shook his head. â€Å"The burn is far too clean.† Rachel glanced at Tolland. The oceanographer nodded. â€Å"Sorry, I’ve had some experience with volcanoes, both above and below water. Corky’s right. Volcanic ejecta is penetrated by dozens of toxins-carbon dioxide, sulfur dioxide, hydrogen sulfide, hydrochloric acid-all of which would have been detected in our electronic scans. That fusion crust, whether we like it or not, is the result of a clean atmospheric friction burn.† Rachel sighed, looking back out the window. A clean burn. The phrase stuck with her. She turned back to Tolland. â€Å"What do you mean by a clean burn?† He shrugged. â€Å"Simply that under an electron microscope, we see no remnants of fuel elements, so we know heating was caused by kinetic energy and friction, rather than chemical or nuclear ingredients.† â€Å"If you didn’t find any foreign fuel elements, what did you find? Specifically, what was the composition of the fusion crust?† â€Å"We found,† Corky said, â€Å"exactly what we expected to find. Pure atmospheric elements. Nitrogen, oxygen, hydrogen. No petroleums. No sulfurs. No volcanic acids. Nothing peculiar. All the stuff we see when meteorites fall through the atmosphere.† Rachel leaned back in her seat, her thoughts focusing now. How to cite Deception Point Page 72, Essay examples

Do People Have The Right To Choose free essay sample

When Essay, Research Paper Hickey 1 What precisely is euthanasia? There are many signifiers of this pattern, including physician assisted sucide, active mercy killing, and inactive mercy killing. In one commendation, mercy killing is the pattern of stoping a individuals life. Euthanasia is practiced worldwide be it legitimate or extremely illegal. Along with our apprehension and acception of mercy killing in todays # 8217 ; society, comes the unreciprocated inquiry, do people have the right to take when to decease? Euthanasia, besides known as clemency violent death, is the pattern of stoping life in order to give release from incurable agony or disease. The word comes form the Hellenic for an easy decease. Euthanasia, technically, refers to assisting patients end their ain lives and does non use to halting life prolonging interventions such as inhalators, or a bash non revive order. ( Glossary # 8230 ; ) Euthanasia can be active or inactive. Active mercy killing agencies that a doctor or other individuals involved with the attention of a patient, takes a calculated action to kill. We will write a custom essay sample on Do People Have The Right To Choose or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Administering an overdose of any prescribed drug is considered active mercy killing. Passive mercy killing agencies allowing a patient dice by manner of the deficiency of intervention, or suspending intervention that has begun. Examples of passive mercy killing include taking patients off a inhalator or taking other life-support systems. Stoping the nutrient Hickey 2 supply, normally occurs in the aged with intavenous devices. ( International # 8230 ; ) A great trade of the contention environing mercy killing comes from the determination procedure. Who decides if a patient is to decease? This issue has non been established lawfully in the United States. The affair is left to province jurisprudence, which normally allows the doctor in charge to propose the option of decease to a patients relatives, particularly if the patient is encephalon dead. ( Euthanasia # 8230 ; ) In an effort to do determinations about when their ain lives should stop, several terminally sick patients in the early 1990 # 8217 ; s used a controversial self-destruction device, developed by Dr. Jack Kevorkian, to stop their lives. This device was created from bit aluminium, a plaything auto, and other garbages scavenged from garage gross revenues and flea markets. The device consisted of a needle which was inserted into the arm of the patient get downing the endovenous flow of a toxicant solution. Kevorkian subsequently switched to a more luxuriant machine which consisted of a tightly fitted mask placed over the face, conncected to a C monoxide case shot. Kevorkian has been involved in 27 deceases to day of the month and has neer been convicted of any incorrect making. ( The Real # 8230 ; ) In parts of Europe, the determination devising procedure has go really flexible. Even in instances where the patients are Hickey 3 non encephalon dead, patients have been put to decease without their consent, at the petition of relations, or at the insisting of doctors. Many instances of nonvoluntary mercy killing affect older people or newborn babies. This is believed to be caused by the # 8220 ; non worthy of life # 8221 ; construct practiced in Nazi Germany ( 1933-45 ) . ( Nazism ) In states where nonvoluntary mercy killing is non legal, the tribunal systems have proven to be really indulgent in covering with medical personel who pattern it. In the Neatherlands and Japan, for illustration, if doctors follow certain guidlines they may transport out mercy violent deaths on terminally sick people. Courts have besides proven to be slightly indulgent with friends or relations who have assisted terminally ill patients to decease. ( Flynn 1-2 ) Euthanasia may look like a dignified manner of death, and in one commendation is described as painlessly seting to decease people who have incurable, painful, or straitening dieseases or disablements. This definition has proven false nevertheless. When a individual is killed with drugs ( deadly injection ) there organic structure frequently has violent paroxysms and musculus cramps. This is by no means a peaceable or dignified manner of deceasing. Besides, if a patient is non killed by the drugs administered to them, so they are frequently times suffocated with a plastic bag by the go toing doctor. ( International Anti # 8230 ; ) Hickey 4 Many physicians are opposed to the legilization of mercy killing. They believe that it is contrary to the full Hippocratic Oath which states, # 8220 ; # 8230 ; I will follow that system of regimen which, harmonizing to my ability and judgement, I see for the benefit of my patients # 8230 ; I will give no lifelessly medical specialty to any one if asked, nor suggest any such advocate # 8230 ; # 8221 ; One doctor provinces, # 8220 ; It ( mercy killing ) would gnaw trust between terminally sick patients and their physicians. # 8221 ; He farther goes on to province that, # 8220 ; Alternatively of therapists, physicians would go traders in decease # 8230 ; As a physician, I would non desire the province stating me to make away with somebody. # 8221 ; ( Risley 1-2 ) Mercy violent death is lawfully considered slaying in the United States, whether it involves shooting person with a drug to # 8220 ; hasten decease # 8221 ; or striping the individual of foods necessary to maintain him or her alive. But most provinces including Iowa, now have Torahs allowing # 8220 ; drawing the stopper # 8221 ; on person who has signed a papers stating he or she does non desire life prolonged by unreal agencies. This papers is called a bash non revive order. The papers provinces if a patients # 8217 ; bosom stops whipping, cardiorespiratory resuscitation will non be performed to protract life. ( Can We # 8230 ; ) Oregon has a # 8220 ; Death With Dignity Act # 8221 ; which states, # 8220 ; An Hickey 5 grownup who is capable and a occupant of Oregon may originate a written petition for medicine. The individual must be declared terminally ill by an go toing doctor. The individual must besides me declared terminally ill by a consultin doctor. The individual must recieve guidance to be certain of mental compitence. The go toing physician must inquire the patient to notify next of family. The individuals # 8217 ; medical records must be exhaustively reviewed. # 8221 ; This helps to do certain that all participants of this plan are sound of head and terminally ill. ( The Oregon # 8230 ; ) Euthanasia is explicitly criminalized in 35 provinces. Nine provinces criminalize assisted sucicide through common jurisprudence. ( Alabama, Idaho, Maryland, Massachusetts, Michigan, Nevada, South Carolina, Vermont, West Virginia ) Three provinces have abolished the common jurisprudence of offenses and do non hold legislative acts criminalizing aided self-destruction. ( North Carolina, Utah, Wyoming ) In Ohio, that province # 8217 ; s supreme tribunal ruled that aided self-destruction is non a offense. Merely the province of Oregon licenses doctor assisted suicide. If a doctor is convicted of any incorrect making in relation to the decease of a patient which is lawfully, ethically, or morally incorrect they may hold there liscense to pattern medical specialty revoked. ( Assisted suicide # 8230 ; )

Monday, May 4, 2020

Pharmaceutical Isolator Mode of Operation

Question: Describe about the Pharmaceutical Isolator for Mode of Operation. Answer: Design and operation of Isolator Systems: Isolators are designed to provide continuous and total isolation of the internal area of the isolator form the external environment. Following are the design considerations for the isolators : size, materials, mode of operation (manual or automatic), ergonomic mock up, material compatibility with the product to be sterilized, type of air flow (laminar or turbulent), control systems for the operation, transferability of equipment and type of products (tested or produced). Isolators are also designed to separate internal area from its operators also. Isolators work on the principle of the positive pressure. Full wall and considerable overpressure is useful in the physical and aerodynamic separation of the separation of the internal components form the external environment. There are two types of designs of isolator are available like closed and open operation. Isolators with closed design use aseptic connection to transfer material to auxiliary equipment. Isolators with closed design r emain closed during its operation. Isolators with open design possess openings for the ingress or outgress of the material. These openings are specifically designed using continuous overpressure to avoid entry of contamination inside the isolator chamber. Isolators with positive pressure design are being widely used and isolators with negative pressure design are being used for handling toxic products. Designs of the isolators with negative pressure are complicated because these types of isolators should satisfy two objectives. These objectives are sterility of the drugs inside the isolator and protection of the operator form the toxic material inside the isolator. Isolators with negative pressure are designed to have special buffer zone. This buffer zone can be used as exhaust for both incoming air in the room and outgoing positive pressure air. By virtue of this, sterile product gets protection from the contaminated air (Midcalf, 2004; Agalloco and Akers, 2016). Advantages: Advantages of the isolator system include: capability to sustain sterility of the equipment for considerably longer duration of time, isolator system is comparatively less expensive in terms of operation cost as compared to the other system like clean room, there are very less chances of sterility false positives due to use of isolator system and there is no requirement of gowning to the operator while using isolator system. Operating cost of isolator is lower as compared to the nonbarrier system. Isolators produce less environmental contamination as compared to the traditional cleanroom. Speed of air and exchange of air is also less in isolator as compared to the traditional cleanroom. This helps isolators in producing less environmental contamination as compared to the cleanroom. In terms of biodecontamination also, isolator has more advantage as compared to the cleanroom. In isolator, only drug and excipients used for the manufacturing comes in direct contact with the operating sy stem. On the other hand, in case of cleanroom human intervention is more in operating system Disadvantages: These isolators have higher capital cost as compared to the non-barrier systems. Time for the qualification of isolators is more as compared to the conventional cleanrooms. It reflects, there is need of additional requirements for qualification of isolator and there is no technical hurdle in its qualification. Isolators have limited flexibility and for its installation there is requirement of significant planning (Agalloco and Carleton, 2007; Coles, 2004). Sterilization processes and its recommendations: Different methods of sterilization used in pharmaceutical industry are dry heat sterilization, chemical sterilization, radiation sterilization and filtration sterilization. Dry heat sterilization kills microorganisms by denaturing proteins and nucleic acids. This dry heat sterilization is simple and cost effective method of sterilization of pharmaceutical products. This method can be useful for the sterilization of glasswares, non-aqueous thermostable liquids and thermostable powders. In radiation sterilization, ionizing and non-ionizing radiation like gamma and X rays can be used. These radiations create free hydrogen radicals, hydroxyl radicals and peroxide radicals which cause intracellular damage to microorganisms and kill them. UV radiation has the capacity to reduce airborne contamination in room by approximately 90 % during the period of 30 minutes. Pharmaceutical powders are more resistant to degradation by ionizing radiation as compared to the pharmaceutical liquids. Radiati on sterilization can be very useful in the sterilization of the thermolabile products like penicillin, streptomycin, thiamine, and riboflavin. Chemical sterilization incorporates use of exposure of materials to be sterilized to the gases like ethylene oxide, formaldehyde, glutaraldehyde and propylene oxide. Ethylene oxide is the most common sterilizing agent used and it acts by the alkylation. Ethylene oxide approximately takes 2 to 5 h at 55C to complete sterilization process. Ethylene oxide is specifically used for the sterilization of the gloves, plastic syringes and disposable needles. Ethylene oxide can be used to sterilize thermolabile pharmaceutical products like penicillin. However, products like thiamine, streptomycin and riboflavin lose potency upon exposure to the ethylene oxide. Filtration sterilization is widely used method for the sterilization of thermolabile products which gets degraded due to heat exposure of other method of sterilization. Filtration sterilization m ethods dont kill the bacteria but remove the bacteria form the material to be sterilized. In filtration sterilization method, material to be sterilized passed through the sterile filter and immediately transferred to the sterile container. Prefiltration of pharmaceutical products can be performed by depth and surface filtration to remove large particles. Different types of filters can be combined together for the effective sterilization. Filtration sterilization can be effectively utilized for the filtration of ophthalmic solutions and biological products. It can also be used for the sterilization of the air and gases to be supplied to aseptic area. Restricted Access Barriers (RABs) are designed to augment the aseptic operations to be carried out in the clean room. Mobile clean room can be used to carry out aseptic operations with more flexibility in the location (Aulton and Taylor, 2013; Jasti and Ghosh, 2004). Environmental monitoring and integrity testing: There is the provision of both viable and non-viable particle monitoring in the isolator system. Both viable and non-viable particle monitoring are the essential components of the isolator. These are not essential components of the sterility test isolator, however it is getting popularity in the recent times. Contamination control can be effectively controlled by the environmental monitoring. Shift of gloves use form the neoprene gloves to the hypalon gloves have dramatically decreased the contamination in case of isolators. In modern isolators, contamination due to gloves is in the same level of the airborne contamination recovery which is a measure of environmental monitoring. As there is very low level of contamination in isolators, intensity of environmental monitoring is very high. For finding small quantity, it is mandatory to evaluate more precisely. Due to difficulty in measurement of zero contamination and due to limitations of limit of detection (LOD), it is difficult to pe rform environmental monitoring in isolators. Isolator environment is extremely clean and there is possibility of getting contamination in not more than 10000 samples. It is not perfect to say isolators are sterile but these are safe enough. Approximately 1 ml sample is required over a period of four hours for the environmental monitoring in case of isolators. Active air sampling is more suitable as compared to the settle plates for environmental monitoring in case of isolators. Surface samples decontaminated with the Vapor-Phase Hydrogen Peroxide are not suitable because these samples are not going to give any type of results. Physical measures like air filtration system and pressure differentials are more valuable as compared to the evaluation of microbial contamination. Isolator performance can be more effectively monitored by evaluating total particulate count as compared to the microbial contamination. Environmental monitoring doesnt give exact data for the sterility. There is e xistence of pathogens which cant be detected by the environmental monitoring. Few pathogens exist in the environment, which are viable but cant be culturable. It reflects, these pathogens have metabolic activity but difficult to culture them (Agalloco and Akers, 2006; Katayama et al., 2008). References: Agalloco, J., and Akers, J. (2016). Advanced Aseptic Processing Technology. CRC Press. Agalloco, J. P., and Carleton, F. J. (2007). Validation of Pharmaceutical Processes. CRC Press. Agalloco, J., and Akers, J. (2006). Simplified Risk Analysis for Aseptic Processing: The Akers-Agalloco Method. Pharmaceutical Technology, 30(7), pp. 60-76. Aulton, M.E. and Taylor, K. M.G. (2013). Aulton's Pharmaceutics: The Design and Manufacture of Medicines. CRC Press LLC. Coles, T. (2004). Isolation Technology: A Practical Guide. CRC Press. Jasti, B. R. and Ghosh, T. K. (2004). Theory and Practice of Contemporary Pharmaceutics. CRC Press. Katayama, H., et al., (2008). Proposal for a New Categorization of Aseptic Processing Facilities Based on Risk Assessment Scores. PDA Journal of Pharmaceutical Science and Technology, 62(4), pp. 235-243. Midcalf, B. (2004). Pharmaceutical Isolators: A Guide to Their Application, Design and Control. Pharmaceutical Press.